Record Display for the EPA National Library Catalog

RECORD NUMBER: 31 OF 42

OLS Field Name OLS Field Data
Main Title Studies on the Percutaneous Absorption of Parathion and Paraoxon, III. Rate of Absorption of Parathion.
Author Fredriksson., Torsten ;
CORP Author Communicable Disease Center, Atlanta, Ga.
Year Published 1961
Stock Number PB-280 570; PB-280 565
Additional Subjects Absorption(Biology) ; Pesticides ; Insecticides ; Skin(Anatomy) ; Measurement ; Humans ; Laboratory animals ; In vivo analysis ; Experimental data ; Cats ; Insecticides ; Tables(Data) ; Labeled substances ; Cholinesterase inhibitors ; Physiology ; Phosphorus organic compounds ; Reprints ; Parathion ; Phosphoric acid/(diethyl-ester)-(nitrophenyl-ester) ; Bioaccumulation ; Environmental health ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB-280 570 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 10p
Abstract
The rate of percutaneous absorption of parathion has been estimated in vivo by following the disappearance from a topical deposit of 32P-labelled material in the cat. There was a definite tendency towards inhibition of plasma cholinesterase activity in two cats, while a third animal failed to show this. The amount of radioactivity in the blood five hours after the application corresponded to 0.02 to 0.04 micrograms parathion per ml. It was concluded that parathion is very slowly absorbed, which makes this compound very unsuitable as a model substance in studies of the process of percutaneous absorption. The results have been discussed with special regard to experimental errors involved and to practical implications.
Notes
Included in PB-280 565,Journal articles on toxicology. Group 12.