Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Evaluation of Stable Labeled Compounds as Internal Standards for Quantitative GC/MS Determinations.
Author Colby, B. N. ;
CORP Author S-Cubed, La Jolla, CA.;Industrial Environmental Research Lab., Research Triangle Park, NC.
Year Published 1983
Report Number EPA-68-02-3153; EPA-600/2-83-127;
Stock Number PB84-127711
Additional Subjects Isotopic labeling ; Labeled substances ; Water analysis ; Standards ; Gas chromatography ; Mass spectroscopy ; Industrial wastes ; Cost analysis ; Water pollution ; Sewage ; Samples ; pH ; Bases ; Deuterium compounds ; Concentration(Composition) ; Traps ; Acids ; Water pollution detection ; Volatile organic compounds ; EPA method 1624 ; EPA method 1625
Library Call Number Additional Info Location Last
NTIS  PB84-127711 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 159p
The report gives results of an investigation of the use of stable isotopically labeled compounds as internal standards for quantitative isotope dilution GC/MS determinations. The availability of labeled compounds and the costs associated with using them for routine analyses were evaluated using the volatile, acid, and base/neutral fraction priority pollutants as a target component base. About 75 percent of these compounds are available as appropriate stable isotopically labeled analogs. Incorporating the stable labeled compounds as part of an analysis protocol is expected to decrease overall analysis costs by 30-70 percent when recommended quality assurance procedures are employed. Fundamental approaches to measurement parameter selection were identified which indicate the best ion fragment masses to measure, the best labeled compound spiking concentration, and the most appropriate data reduction methods.