Record Display for the EPA National Library Catalog
RECORD NUMBER: 14 OF 1722
|OLS Field Name||OLS Field Data|
|Main Title||2,4-Pentanedione: Fourteen Week Vapor Inhalation Study in Rats with Cover Letter dated 07/29/85 and EPA Acknowledgement Letter.|
|CORP Author||Union Carbide Corp., Danbury, CT. ;Mellon Inst.-Union Carbide Corp., Export, PA. Bushy Run Research Center.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Rats ; Vapors ; Inhalation ; Mortality ; Brain ; Gliosis ; Body weight ; Blood analysis ; Food consumption ; Water consumption ; Pathology ; Organ weight ; Histopathology ; Urinalysis ; Statistical procedure ; 2,4-pentanedione ; Vapor inhalation ; Degenerative changes ; C(sub 5H)(sub 8)(sub 2) ; Necropy|
Enclosed for your information is a report of a 14-week vapor inhalation study with rats concerning 2,4-pentanedione C (sub 5) H (sub 8) O (sub 2), CAS No. 123-54-6. The test results confirm previously reported findings that subchronic recurrent exposure of rats to 2, 4-pentanedione at high doses may cause a high level of mortality, degenerative changes in the brain and thymus in animals that died, and gliosis in some survivors. Although Union Carbide does not regard this information as reportable under Section 8(e) of the Toxic Substances Control Act, in light of EPA's position on other Section 8(e) judgments by Union Carbide, we are submitting the study for your information.