Record Display for the EPA National Library Catalog

RECORD NUMBER: 20 OF 108

OLS Field Name OLS Field Data
Main Title Compartmental Models with Spatial Diffusion: Estimation for Bone-Seeking Tracers.
Author Marcus, A. H. ;
CORP Author Washington State Univ., Pullman. Dept. of Pure and Applied Mathematics.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1983
Report Number EPA/600/J-83/343;
Stock Number PB86-208816
Additional Subjects Models ; Bones ; Diffusion ; Isotopic labeling ; Reprints ;
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB86-208816 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 19p
Abstract
A compartmentlike model is developed for tracers in which bone-volume diffusion plays an important role in body distribution (e.g. bone-volume-seeking metals). The model requires solution of an infinite eigensystem. Approximations are presented for cylindrical diffusion in canalicular territory. An application to lead metabolism in beagle dogs suggests that finite truncation of the system of equations provides an adequate approximation for routine use in computer programs for compartmental-parameter estimation. The model is consistent with both power-law and exponential mixture retention functions.