Record Display for the EPA National Library Catalog

RECORD NUMBER: 499 OF 1580

OLS Field Name OLS Field Data
Main Title Estimating limiting risk levels from orally ingested DDT and dieldrin using an up-dated version of the Mantel-Bryan procedure /
Author Mantel, Nathan.
CORP Author George Washington Univ., Washington, D.C.;Environmental Protection Agency, Washington, D.C. Office of Toxic Substances.
Publisher Office of Toxic Substances, Environmental Protection Agency,
Year Published 1974
Report Number P4-01-02962; EPA 560/5-75-003
Stock Number PB-243 009
OCLC Number 41993656
Subjects Dieldrin. ; DDT (Insecticide) ; Pesticides. ; Dichlorodiphenyltrichloroethane
Additional Subjects Carcinogens ; DDT ; Dieldrin ; Laboratory animals ; Malignant neoplasms ; Ingestion(Biology) ; Dosage ; Experimental data ; Insecticides ; Chlorine organic compounds ; Liver ; Statistical analysis ; Biostatistics ; Tables(Data)
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=91012FEV.PDF
Local Library Info
Library Local Subject Local Note
EKB EKB copy is NTIS an reproduction.
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJBD ARCHIVE EPA 560-5-75-003 Headquarters Library/Washington,DC 09/22/2014
EJBD  EPA 560-5-75-003 Headquarters Library/Washington,DC 09/22/2014
EKBD  EPA-560/5-75-003 Research Triangle Park Library/RTP, NC 06/06/2003
ELBD RPS EPA 560-5-75-003 repository copy AWBERC Library/Cincinnati,OH 05/22/2018
NTIS  PB-243 009 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 17 pages : tables ; 28 cm
Abstract
Mathematical extrapolations of the upper limits on risk of cancer at various low levels of exposure to dieldrin and DDT are presented. The statistical model used is that described by Mantel, et al., Cancer Research, 35, 865-872, 1975, the so-called 'updated' Mantel-Bryan procedure. The data upon which the extrapolations are based are derived from the studies by Tomatis, et al., International Journal of Cancer, 10, 489-506, 1972 for DDT and by Walker, et al. Food and Cosmetics Toxicology, 11, 415-432, 1972 for dieldrin. Several alternative methods of treating the data are presented, and pesticide levels associated with various levels of risk are estimated. Certain precautions which must be observed in applying the 'updated' Mantel-Bryan technique are discussed.
Notes
"Prepared for the Office of Toxic Substances, Environmental Protection Agency." "Project Officer: Michael J. Prival." "Contract no. P4-01-02962." Bound with Supplement of the same title, dated December 27, 1974. Contract # P5-01-2598-J.