Record Display for the EPA National Library Catalog

RECORD NUMBER: 1557 OF 1580

OLS Field Name OLS Field Data
Main Title Urinary Excretion of Insecticide Metabolites, Excretion of Para-nitrophenol and DDA as Indicators of Exposure to Parathion and DDT.
Author Wolfe, Homer R. ; Durham, William F. ; Armstrong., John F. ;
CORP Author Food and Drug Administration, Chamblee, Ga.
Year Published 1970
Stock Number PB-280 836
Additional Subjects Toxicology ; Pesticides ; Nitrophenols ; Industrial medicine ; Insecticides ; DDT ; Excretion ; Phosphorus organic compounds ; Urine ; Exposure ; Temperature ; Toxic substances ; Reprints ; Metabolites ; Acetic acid/bis(chlorophenyl) ; Occupational safety and health ; Parathion
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB-280 836 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 6p
Abstract
The urinary excretion of p-nitrophenol and of dichlorodiphenylacetic acid (DDA) was measured in spraymen applying formulations containing both parathion and DDT. In each instance, excretory level of metabolite correlated well with exposure to the pesticide. Para-nitrophenol excretion levels showed changes of greater magnitude in response to a specific exposure than did DDA excreation. However, in general the excretory patterns for p-nitrophenol and DDA were similar. Both metabolites reached peak levels at about the same time interval (p-nitrophenol, 8.7 hours; DDA, 10.1 hours) after exposure began. Excretion of both p-nitrophenol and DDA tended to increase with an increase in ambient temperature. Excretion curves for both metabolites showed diurnal variation during the period after exposure had ended. On the average for a specific exposure, more parathion-derived material than DDT-derived material was recovered in the urine.