Record Display for the EPA National Library Catalog
RECORD NUMBER: 219 OF 314Main Title | Penetration of the Blood-Brain-Cerebral Spinal Fluid Barrier by DDT. | |||||||||||
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Author | Morrison., Glenn ; | |||||||||||
CORP Author | Environmental Protection Agency, Chamblee, Ga. Office of Pesticides Programs. | |||||||||||
Year Published | 1971 | |||||||||||
Stock Number | PB-279 728 | |||||||||||
Additional Subjects | Insecticides ; DDT ; Toxicology ; Blood ; Brain ; Cerebrospinal fluid ; Central nervous system ; Chlorine organic compounds ; Rats ; Dosage ; Ingestion(Biology) ; Laboratory animals ; Experimental data ; Tables(Data) ; Physiological effects ; Concentration(Composition) ; Tissues(Biology) ; Bioassay ; Reprints ; Toxic substances ; Convulsions | |||||||||||
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Collation | 7p | |||||||||||
Abstract | The central nervous system (CNS) is a unique organ system in that it not only receives a rich vascular supply, but, in addition, cological information about any neurotoxic compound includes ascertaining the absolute and relative anounts of the compound in these three separate, but intimately related, compartments (blood, CSF, brain) at a given time after the administration of an intoxicating dose of the compound. The present study was undertaken to obtain this information for the organochlorine compound, p,p'-DDT (2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane). |