Record Display for the EPA National Library Catalog
RECORD NUMBER: 220 OF 397Main Title | Identification of Five Unreported Lindane Metabolites Recovered from Rat Urine. | |||||||||||
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Author | Chadwick, R. W. ; Freal., J. J. ; | |||||||||||
CORP Author | Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab. | |||||||||||
Year Published | 1972 | |||||||||||
Stock Number | PB-275 925 | |||||||||||
Additional Subjects | Chlorobenzenes ; Insecticides ; Pesticides ; Chlorine aromatic compounds ; Identifying ; Rats ; Urine ; Experimental data ; Laboratory animals ; Tables(Data) ; Diet ; Metabolism ; Isolation ; Ingestion(Biology) ; Excretion ; Metabolites ; Lindane ; Reprints | |||||||||||
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Collation | 10p | |||||||||||
Abstract | Previously unreported metabolites from the urine of rats fed lindane have been identified as 3,4-dichlorophenol, 2,4,6-trichlorophenol, 2,3,4,5-tetrachlorophenol, 2,3,4,6-tetrachlorophenol and 2,3,4,5,6-pentachloro-2-cyclohexen-1-ol. While the 3,4-dichlorophenol is a minor metabolite, the others are excreted in greater quantities than either 2,3,5- or 2,4,5-trichlorophenol, previously identified lindane metabolites. The excretion of tetrachlorophenols and PCCOL require a revision in the currently accepted theory regarding the metabolism of lindane by mammals. |