Record Display for the EPA National Library Catalog

RECORD NUMBER: 41 OF 338

OLS Field Name OLS Field Data
Main Title Chronic Ingestion of Cadmium and/or Tritium. II. Effects on Growth, Development, and Reproductive Function.
Author Laskey, J. W. ; Rehnberg, G. L. ; Favor, M. J. ; Cahill, D. F. ; Pietrzak-Flis, Z. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1979
Report Number EPA-600/J-80-250;
Stock Number PB81-191926
Additional Subjects Cadmium ; Tritium ; Toxicology ; Growth ; Reproduction(Biology) ; Rats ; Laboratory animals ; Evaluation ; Metals ; Ingestion(Biology) ; Reprints ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB81-191926 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 12p
Abstract
The effects of chronic low-level exposure to cadmium (Cd) and/or tritium (HTO) on the growth and reproduction were evaluated in Sprague-Dawley rats. Cadmium exposure levels ranged from less than 0.1 to 5.0 ppm as CdCl2 in the drinking water, while HTO concentrations ranged from less than 0.1 to 13.0 microns Ci/ml. Exposures were started with conception of the first generation. Both insults, at the higher doses, resulted in depressed adult body weight. Chronic Cd exposure caused liver weight decrements and a decrease in sperm counts. HTO effects were manifested in a depression of several reproductive parameters and brain weights in the F2 neonates. Synergistic effects of simultaneous exposure were minimal.