Record Display for the EPA National Library Catalog

RECORD NUMBER: 21 OF 338

OLS Field Name OLS Field Data
Main Title Barium Bioavailability as the Chloride, Sulfate, or Carbonate Salt in the Rat.
Author McCauley, P. T. ; Washington, I. S. ;
CORP Author Health Effects Research Lab., Cincinnati, OH.
Year Published 1983
Report Number EPA-600/J-83-048;
Stock Number PB84-101799
Additional Subjects Barium ; Toxicology ; Rats ; Laboratory animals ; Concentration(Composition) ; Diets ; Ingestion(Biology) ; Biological availability ; Drinking water
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB84-101799 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 11p
Abstract
This study was conducted to determine how the bioavailability of a low concentration of barium (Ba) in drinking water is affected by anion speciation. Male Sprague Dawley rats weighing 250-300 grams were maintained on a diet of less than 1 mg Ba/kg of food for at least 1 month prior to experimentation. Rats were given 10.0 mg Ba131/liter as sulfate (SO4), chloride (C1), or carbonate (CO3) at pH 7.0. Animals were sacrificed at 2, 5, 10, 20, 30, 60, and 120 minutes and 24 hours after intubation. When 131Ba was administered, as C1, 131Ba in blood rose linearly for 10 minutes and then less rapidly until the highest number of counts was measured at 60 minutes. At 24 hours 131Ba was still at 90% of peak levels. In eye, 131Ba increased linearly for 1 hour.