Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Effects of Microwave-Exposure and Temperature on Survival of Mice Infected with 'Streptococcus pneumoniae' (Journal Version).
Author Liddle, C. G. ; Putnam, J. P. ; Lewter, O. H. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Publisher 1987
Year Published 1987
Report Number EPA/600/J-87/424;
Stock Number PB89-105977
Additional Subjects Hyperthermia ; Streptococcus pneumoniae ; Bacterial infections ; Microwaves ; Induced hyperthermia ; Temperature ; Laboratory animals ; Exposure ; Survival ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB89-105977 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/14/1989
Collation 10p
Female CD-1 mice were injected with an LD50 dose of Streptococcus pneumoniae and then exposed to 2.45 GHz (CW) microwave radiation at an incident power density of 10 mW/cm2 (SAR approximately equals 6.8 W/kg), 4 h/d for 5 d at ambient temperatures of 19, 22, 25, 28, 31, 34, 37 and 40 degs. C. The results showed that survival of sham exposed animals increased as ambient temperature increased until 37 degs. C when the thermoregulatory capacity of the animals was exceeded and deaths due to hyperthermia occurred. Survival of microwave exposed animals was significantly greater than the shams (approximately 20 percent) at each ambient temperature below 34 degs. C. An analysis of the data suggests that the hyperthermia from microwaves may be more effective in increasing survival than conventional hyperthermia. The results indicate that microwave radiation may be beneficial to infected animals at low and moderate ambient temperatures, but detrimental when combined with high ambient temperatures.