| Main Title |
Sensitivity, Specificity and Accuracy of the Arabidopsis Assay in the Identification of Carcinogens. |
| Author |
Redei, G. P. ;
Acedo, G. N. ;
Andhu, S. S. ;
|
| CORP Author |
Missouri Univ.-Columbia.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1984 |
| Report Number |
EPA-R-807892; EPA-600/D-84-105; |
| Stock Number |
PB84-182195 |
| Additional Subjects |
Carcinogens ;
Bioassay ;
Bacteria ;
In vitro analysis ;
In vivo analysis ;
Sensitivity ;
Mutagens ;
Identifying ;
Accuracy ;
Arabidopsis multilocus ;
Bioindicators
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB84-182195 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
33p |
| Abstract |
The paper compares the sensitivity, specificity and accuracy of Arabidopsis multilocus assay with several other in vitro and in vivo bioassays. Sensitivity was defined as a percentage of the carcinogens correctly identified as mutagens. Specificity was calculated by multiplying with 100 the fraction of the number correctly identified 'non-carcinogens'/total number of 'non-carcinogens' unambiguously classified. Accuracy represents the fraction of the correct answers/all unambiguous test, multiplied with 100. These parameters were estimated in Arabidopsis by testing 37 carcinogen/non-carcinogen pairs of chemicals. The overall sensitivity of Arabidopsis assay was higher than any of the bioassays employed in the Internation Collaborative Program. |
