Record Display for the EPA National Library Catalog
RECORD NUMBER: 7 OF 10Main Title | Oral and Dermal Toxicity of Hexachlorophene in Rats. | |||||||||||
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Author | Gaines, T. B. ; Kimbrough., R. D. ; | |||||||||||
CORP Author | Environmental Protection Agency, Chamblee, Ga. Office of Pesticides Programs. | |||||||||||
Year Published | 1971 | |||||||||||
Stock Number | PB-277 605 | |||||||||||
Additional Subjects | Toxicology ; Pesticides ; Bactericides ; Rats ; Sex ; Lethal dosage ; Ingestion(Biology) ; Diets ; Central nervous system ; Paralysis ; Reproduction(Biology) ; Laboratory animals ; Experimental data ; Toxicity ; Reprints ; Hexachlorophene ; Toxic substances | |||||||||||
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Collation | 1p | |||||||||||
Abstract | The toxicity of hexachlorophene, a widely used fungicidal and bactericidal agent, was studied in Sherman strain rats. The acute oral LD50 for hexachlorophene in peanut oil solution was 56 mg kg in female rats and 66 mg kg in males. Adult female rats fed 500 ppm hexachlorophene in the diet for 97 days developed paralysis in the hindquarters: 1 of 10 rats died. |