Record Display for the EPA National Library Catalog
RECORD NUMBER: 474 OF 1079| Main Title | Metabolic Activation of 3-(2-Chloroethoxy)-1,2-Dichloropropene: A Mutagen Structurally Related to Diallate, Triallate, and Sulfallate. | |||||||||||
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| Author | Distlerath, L. M. ; Loper, J. C. ; Tabor, M. W. ; | |||||||||||
| CORP Author | Cincinnati Univ. Medical Center, OH.;Health Effects Research Lab., Research Triangle Park, NC. | |||||||||||
| Year Published | 1985 | |||||||||||
| Report Number | EPA-R-808603; EPA/600/J-85/138; | |||||||||||
| Stock Number | PB85-249837 | |||||||||||
| Additional Subjects | Water pollution ; Salmonella ; Herbicides ; Metabolism ; Mutagens ; Potable water ; Carbamates ; Chlorine organic compounds ; Allyl chloride ; Ethers ; Acroleins ; Chlorine aliphate compounds ; Biphenyl ; Aromatic compounds ; Activation ; Extraction ; Chloromethanes ; Reprints ; Mutagenicity tests ; Propenel dichloro-chloroethoxy | |||||||||||
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| Collation | 11p | |||||||||||
| Abstract | 3-(2-Chloroethoxy)-1,2-dichloropropene (CP), a Samonella promutagen which was recently isolated from a sample of residue organics previously concentrated from drinking water, is structurally related to three other chlorinated promutagens, the S-chloroallyl thiocarbamate herbicides diallate, triallate and sulfollate. These four chloroallyl ether compounds were found to be similar with respect to strain specificity, potency and requirement for specific metabolic activation. (Copyright (c) 1985 Alan R. Liss, Inc.) |