Record Display for the EPA National Library Catalog

RECORD NUMBER: 206 OF 1146

OLS Field Name OLS Field Data
Main Title Detection of mutagenic properties of pesticides used in commercial corn production. {MICROFICHE}
Author Plewa, Michael J. ; Gentile, James M.
CORP Author Illinois Univ. at Urbana-Champaign. Inst. for Environmental Studies.;Health Effects Research Lab., Research Triangle Park, NC. ;Hope Coll., Holland, MI. Dept. of Biology.
Publisher Institute for Environmental Studies, University of Illinois for US Environmental Protection Agency
Year Published 1983
Report Number EPA-68-02-2704; EPA-600/1-83-006
Stock Number PB83-226118
Subjects Pesticides
Additional Subjects Pesticides ; Corn ; Herbicides ; Toxicology ; Detection ; Bioassay ; Mutations ; Bacteria ; Mutagenesis ; Genotoxicity ; Bioindicators
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB83-226118 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 212 p. : graphs ; 28 cm.
Abstract
This project encompassed the analysis of 21 pesticides and 12 combinations of herbicides for their genotoxic properties. Three genetic assays were employed: reverse mutation in Salmonella typhimurium, gene conversion in S. cerveisiae and reverse mutation in Z. mays. The use of these genetic indicator organisms established a comprehensive data base that resolved a spectrum of genetic damage induced by single agents or by combination of agents. The pesticides were evaluated with the microbial assays directly, after in vitro mammalian microsomal activation and after in vivo plant activation protocols. Finally all the pesticides were tested for their ability to induce mutations in Z. mays under in situ (in field) conditions.
Notes
Supported in part by the U.S. Dept. of the Interior, Office of Water Research and Technology. "EPA600/1-83/006". Microfiche.