Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Radiofrequency Radiation-Induced Calcium Ion Efflux Enhancement from Human and Other Neuroblastoma Cells in Culture (Journal Article).
Author Dutta, S. K. ; Ghosh, B. ; Blackman., C. F. ;
CORP Author Howard Univ., Washington, DC.;Health Effects Research Lab., Research Triangle Park, NC.;Department of Energy, Washington, DC.
Publisher c1989
Year Published 1989
Report Number EPA/600/J-89/230;
Stock Number PB90-146002
Additional Subjects Calcium ; Neuroblastoma ; Radio frequencies ; Exposure ; Amplitude modulation ; Ions ; Cats ; Birds ; Humans ; Reprints ; Radiation effects ; Radiation absorption analysis ; Dose-response relationships ; Chinese hamsters ; Cultured tumor cells
Library Call Number Additional Info Location Last
NTIS  PB90-146002 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/15/1990
Collation 8p
In order to test the generality of radiofrequency-radiation-induced change in alteration of (45)Ca(2+) efflux from avian and feline brain tissues, human neuroblastoma cells were exposed to electromagnetic radiation at 147 MHz, amplitude modulated (AM) at 16 Hz, at specific absorption rates (SAR) of 0.1, 0.05, 0.01, 0.005, 0.001, and 0.0005 W/kg. Significant (45)Ca(2+) efflux was obtained at SAR values of 0.05 and 0.005 W/kg. Enhanced efflux at 0.05 W/kg peaked at the 13-to-16 Hz and at the 57.5-to-60 Hz modulation ranges. A Chinese hamster-mouse hybrid neuroblastoma was also shown to exhibit enhanced radiation-induced (45)Ca(2+) efflux at an SAR of 0.05 W/kg, using 147 MHz, AM at 16 Hz. These results confirm that amplitude-modulated radiofrequency radiation can induce responses in cells of nervous tissue origin from widely different animal species including humans. The results are also consistent with the reports of similar findings in avian and feline brain tissue reported by others and indicate the general nature of the phenomenon. (Copyright (c) 1989 Alan R. Liss, Inc.)