Record Display for the EPA National Library Catalog
RECORD NUMBER: 729 OF 1859Main Title | Fish Subchronic Toxicity Prediction Model for Industrial Organic Chemicals that Produce Narcosis. | |||||||||||
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Author | Call, D. J. ; Brooke, L. T. ; Knuth, M. L. ; Poirier, S. H. ; Hoglund, M. D. ; | |||||||||||
CORP Author | Wisconsin Univ.-Superior. Center for Lake Superior Environmental Studies.;Environmental Research Lab.-Duluth, MN. | |||||||||||
Year Published | 1985 | |||||||||||
Report Number | EPA/600/J-85/197; | |||||||||||
Stock Number | PB86-117330 | |||||||||||
Additional Subjects | Organic compounds ; Minnows ; Toxicity ; Water pollution ; Narcosis ; Industrial wastes ; Halogen organic compounds ; Concentration(Composition) ; Chlorobenzenes ; Exposure ; Larvae ; Embryos ; Survival ; Growth ; Abnormalities ; Mathematical models ; Reprints ; | |||||||||||
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Collation | 8p | |||||||||||
Abstract | A model based on partition coefficient was developed for predicting subchronic toxicities of selected chemicals to fish. Early life stage tests were conducted under flow-through conditions using fathead minnows (Pimephales promelas) as test organisms. Embryos, larvae and juveniles were continuously exposed to chemicals for a total of 31 to 33 d. Test endpoints included egg hatchability, incidence of developmental abnormalities, survival and growth. The 'chronic value' for each test was a point estimate of the maximum acceptable toxicant concentration (MATC), and was determined as the geometric mean of the highest test concentration producing no effect and the lowest concentration significantly (p |