A preliminary investigation of the nature and extent of sediment contamination in the lower Grand River was performed. Three areas in the lower Grand River exceeded sediment quality guidelines for heavy metals and selected organic chemicals. The locations and parameters of concern are listed below: Harbor Island (G20). Exceeds sediment PEL values for chromium, lead, nickel, and DDE in the top core section. Deeper core sections were extensively contaminated with heavy metals. Spring Lake (G6). Exceeds sediment PEL values for chromium, lead, cadmium, nickel, and DDE. Grand Haven (G12). Exceeds sediment PEL values for chromium and nickel. The sediments at this location exhibited a statistically significant level of toxicity to amphipods when compared to the control.