||Asbestos and gastro-intestinal cancer : cell culture studies /
Reiss, B. ;
Weisburger, J. H. ;
Williams, G. M.
||American Health Foundation, Valhalla, NY. Naylor Dana Inst. for Disease Prevention.;Health Effects Research Lab., Cincinnati, OH.
|| Environmental Protection Agency, Office of Research and Development [Office of Health aand Ecological Effects], Health Effects Research Laboratory ; For sale by the National Technical Information Service,
Cell culture. ;
Malignant neoplasms ;
Gastrointestinal system ;
Silicate minerals ;
Air pollution ;
In vitro analysis ;
Cell cltures ;
Toxic substances ;
Environmental health ;
Air polluion effects(Humans) ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||viii, 37 pages : illustrations ; 28 cm.
Three forms of asbestos: amosite, crocidolite, and chrysotile, were assayed for their cytotoxicity and mutagenicity in cell clture. Using embjryonic human intestine derived and adult rat liver derived epitelial cells, the order of toxicity was chrysotile > amosite = crocidolite. Leaching in acid slightly increased the toxicity of amosite and crocidolite and greatly decreased the toxicity of chrysotile. High concentrations of all three asbestos forms were not mutagenic in cultures of rat liver-derived epithelial cells.
Grant no. R-803998-01. July 1979. Includes bibliographical references (pages 32-36). Microfiche.