Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Fate of ingested chrysotile asbestos fiber in the newborn baboon /
Author Hallenbeck, William H., ; Patel-Mandlik, Kusum
Other Authors
Author Title of a Work
Patel-Mandlik, Kusum,
CORP Author Illinois Univ. at the Medical Center, Chicago. School of Public Health.;Health Effects Research Lab., Cincinnati, OH.
Publisher Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory, For sale by the National Technical Information Service.
Year Published 1979
Report Number EPA-600/1-78-069
Stock Number PB-291 686
OCLC Number 04944232
ISBN pbk.
Subjects Asbestos. ; Serpentine. ; Ingestion. ; Interferometers. ; Asbestos--toxicity. ; Papio.
Additional Subjects Asbestos ; Toxicology ; Bioassay ; Dosage ; Infants ; Primates ; Serpentine ; Diets ; Ingestion(Biology) ; Exposure ; Tables(Data) ; Fibers ; Electron microscopy ; Tissues(Biology) ; Evaluation ; Gastrointestinal system ; Kidney ; Spleen ; Liver ; Pathology ; Potable water ; Baboons ; Drinking water ; Papio anubis ; Water pollution effects(Animals)
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 600-1-78-069 Headquarters Library/Washington,DC 01/23/2012
EJBD  EPA 600-1-78-069 c.1 Headquarters Library/Washington,DC 04/21/2014
EKAM  EPA-600/1-78-069 Region 4 Library/Atlanta,GA 12/03/1999
EKBD  EPA-600/1-78-069 Research Triangle Park Library/RTP, NC 06/01/2001
NTIS  PB-291 686 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 07/22/2019
Collation viii, 16 pages : illustrations ; 28 cm
The objective of this research was to determine if orally administered chrysotile asbestos fibers could penetrate through the gastrointestinal tract of the neonate baboon and be recovered in selected tissues. A neonate baboon was given a cumulative dose of 3 to the 13th power chrysotile fibers per kilogram. At the end of a 9-day feeding period test and control animals were sacrificed. The following tissues were collected: kidney, liver, spleen, heart, lymph nodes, urine, blood, and gastrointestinal tract. Many methodological problems were encountered in preparing tissues for evaluation by electron microscopy. After developing a satisfactory preparation technique, tissue samples of kidney cortex, kidney medulla, spleen, and liver were analyzed. Definitive data are presented which demonstrate the recovery of chrysotile asbestos from kidney cortex tissue. Data concerning the kidney medulla, spleen and liver tissues must be considered preliminary as more definitive work is in progress concerning these and other tissues.
Order no. CA-7-3159-J. "EPA-600/1-78-069." Dec. 1978. Includes bibliographical references.