Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Chronic Dietary Administration of Terephthalic Acid with Cover Letter dated 04/24/84.
CORP Author Chemical Industry Inst. of Toxicology, Research Triangle Park, NC.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher Dec 1983
Year Published 1983
Report Number FYI-OTS-0584-0190-SU;
Stock Number OTS-0000190-1
Additional Subjects Terephthalic acid ; Reproduction ; Wistar rats ; Rats ; Experiments ; Food consumption ; Body weight ; Toxicity ; Induced urolithiasis ; CD rats
Library Call Number Additional Info Location Last
NTIS  OTS-0000190-1 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 10/08/2007
Collation 54p
The report contains the results of a two year carcinogenesis bioassay of terephthalic acid which was funded by the Chemical Industry Institute of Toxicology and conducted at IIT Research Institute. Several unusual problems occurred in this study. There was a very high incidence of uterine adenocarcinomas in both control and test female rats and a 100% incidence of cataracts in both test and control males and females. The report speculates that these results may be secondary to continuous lighting for an unknown period prior to the eighteenth month of the study. The etiology of these results and potential effects of these problems on the outcome of the bioassay are unknown.