The Agency's Office of Pesticide Programs (OPP) regulates pesticides to ensure that their use does not pose unreasonable risks to human health or the environment and that exposure to pesticide residues in food is safe. These determinations rely on the process of risk assessment. In assessing risk, the Agency considers all sources of exposure (e.g., food, drinking water, incidental exposure in and around the home, school, etc.) and the inherent toxicity of the pesticide. The purpose of this User's Guide is to provide the reader with a comprehensive discussion and listing of U.S. Environmental Protection Agency (EPA or the Agency), U.S. Department of Agriculture (USDA), and U.S. Food and Drug Administration (FDA) guidance, policy documents, and databases that provide detailed, specific 'how-to' information and/or data on assessing exposure to pesticides from the foods that we eat. To help the reader understand the context of this information, this guide first provides a basic overview of risk assessment for exposure resulting from pesticide residues in food.