Record Display for the EPA National Library Catalog

RECORD NUMBER: 27 OF 256

OLS Field Name OLS Field Data
Main Title Ethyl Acrylate: Inhalation Teratology Study in Rats with Attachments and Cover Letter Dated 07/17/1989 (Sanitized).
CORP Author Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 86-890001351S
Stock Number OTS0520851
Additional Subjects Toxicology ; Health effects ; Ethyl Acrylate (140-88-5) ; Reproduction/fertility Effects ; Teratogenicity ; Mammals ; Rats ; Inhalation ; Toxic substances ; Laboratory animals ; CAS No 140-88-5
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NTIS  OTS0520851 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 49p
Abstract
Developmental toxicity was evaluated in groups of 33 female Sprague-Dawley rats receiving whole-body exposure to ethyl acrylate at vapor concentrations of 0, 50, or 150 ppm, for 6 hours/day on gestation days 6-15, followed by fetal examination on gestation day 21. High-dose dams had decreased body weight gain and food consumption, and increased water consumption. The compound was not embryotoxic or fetotoxic. The was a small increase in fetal malformations in the high-dose group, but the difference was not significant.