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OLS Field Name OLS Field Data
Main Title Ammonia Abatement System for Whole-Body Small Animal Inhalation Exposures to Acid Aerosols.
Author Higuchi, M. A. ; Davies, D. W. ;
CORP Author ManTech Environmental Technology, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. Environmental Toxicology Div.
Publisher c1993
Year Published 1993
Report Number EPA-68-02-4450; EPA/600/J-93/333;
Stock Number PB93-229516
Additional Subjects Laboratory animals ; Excretion ; Ammonia ; Acidity ; Aerosols ; Exposure chambers ; Inhalation ; Clinical trials ; Body fluids ; Feces ; Reprints ; Small animal whole-body ammonia reduction system
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB93-229516 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 11/22/1993
Collation 13p
Abstract
Conducting whole-body acid aerosol inhalation exposures of laboratory animals is complicated by ammonia arising from the excrement of the test animals which is sufficient to completely neutralize much of the acid aerosol. The development of a small animal whole-body ammonia reduction system (SAWBARS) for inhalation exposures was desirable for long-term rodent exposure studies. The removal of ammonia was accomplished by designing and fabricating stainless steel excreta pan manifolds to exhaust ammonia from the pans as it was generated. In addition, all chamber air influent was conditioned by a wet scrubber to remove ambient ammonia, minimizing background levels of the vapor. Total chamber air effluent was exhausted through the excreta pan manifolds. The modification effectively removed up to 99% of the ammonia from the chamber atmosphere when incorporated with daily animal bedding changes during non-exposure periods. (Copyright (c) 1993 Taylor and Francis.)