Record Display for the EPA National Library Catalog

RECORD NUMBER: 50 OF 4772

OLS Field Name OLS Field Data
Main Title A rapid method for estimating log P for organic chemicals /
Author Veith, Gilman D. ; Morris., Richard T.
Other Authors
Author Title of a Work
Morris, Richard T.,
CORP Author Environmental Research Lab.-Duluth, Minn. ;Wisconsin Univ.-Superior.
Publisher Environmental Protection Agency, Office of Research and Development, Environmental Research Laboratory ; For sale by the National Technical Information Service,
Year Published 1978
Report Number EPA-600/3-78-049
Stock Number PB-284 386
OCLC Number 04146579
ISBN pbk.
Subjects Liquid chromatography. ; Logarithms.
Additional Subjects Organic compounds ; Chemical analysis ; Chromatographic analysis ; High temperature tests ; Numerical solutions ; Calibrating ; Solutions ; Laboratory equipment ; Liquid chromatography ; Partition coefficients ; Procedures
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9100T4LP.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJAD  EPA 600/3-78-049 Region 3 Library/Philadelphia, PA 04/16/1993
EJBD ARCHIVE EPA 600-3-78-049 Headquarters Library/Washington,DC 09/22/2014
EKAM  EPA 600/3-78-049 Region 4 Library/Atlanta,GA 05/13/1994
EKBD  EPA-600/3-78-049 Research Triangle Park Library/RTP, NC 08/11/2000
ELDD  EPA-600/3-78-049 3 copies NHEERL/MED Library/Duluth,MN 05/04/2001
EOAD  EPA 600/3-78-049 Region 8 Technical Library/Denver,CO 02/28/2011
EOBD  EPA 600-3-78-049 NEIC Library/Denver,CO 01/14/2000
ERAD  EPA 600/3-78-049 Region 9 Library/San Francisco,CA 10/22/2012
ESAD  EPA 600-3-78-049 Region 10 Library/Seattle,WA 03/23/2010
NTIS  PB-284 386 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation viii, 16 pages : illustrations ; 28 cm.
Abstract
A rapid, inexpensive technique based on reverse-phase high pressure liquid chromatography has been developed to estimate the n-octanol/water partition coefficient of organic chemicals. The system consists of a preparative Micro-Pak C-(R)10 reverse-phase column eluted with a 15 percent water/85 percent methanol solvent flowing at 2 ml/min at room temperature. The chemicals are detected in the eluant with a standard ultraviolet detector or a fraction collector system followed by appropriate analysis of the fractions to determine the retention time of the chemical. A linear calibration of the logarithm of retention time with the logarithm of the partition coefficient (Log P) is attained by using a mixture of benzene, bromobenzene, biphenyl, bibenzyl, pp'DDE, and 2,4,5,2',5' pentachlorobiphenyl as reference standards of known Log P. Chemicals with Log P of approximately 3 elute in less than 10 min whereas those with Log P greater than 5 elute after 20 min.
Notes
Issued May 1978. Includes bibliographical references (page 15).