||Review of EPA's Integrated Risk Information System (IRIS) Process.
||National Research Council, Washington, DC. Division on Earth and Life Studies.; Environmental Protection Agency, Washington, DC.
Chemical assessments ;
Human health ;
Hazard evaluation ;
Toxicologic assessments ;
Environmental contaminants ;
Dose response ;
Integrated Risk Information System(IRIS)
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
In 2011, the National Research Council (NRC) released a report that reviewed the draft health assessment on formaldehyde produced by the US Environmental Protection (EPA) for its Integrated Risk Information System (IRIS). The report recommended improvements in the formaldehyde assessment and in the program responsible for producing the assessment. Congress directed EPA to implement the reports recommendations and then asked the NRC to review the changes that EPA was making (or proposing to make) in response to the recommendations. In the present report, the Committee to Review the IRIS Process first provides an overview of some general issues associated with IRIS assessments. It then addresses evidence identification and evaluation for IRIS assessments and discusses evidence integration for hazard evaluation and methods for calculating reference values and unit risks. It concludes with some overall recommendations and considerations for future directions.