Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Astrovirus-Like, Coronavirus-Like, and Parovirus-Like Particles Detected in the Diarrheal Stools of Beagle Pups.
Author Williams Jr, F. P. ;
CORP Author Health Effects Research Lab., Cincinnati, OH.
Year Published 1980
Report Number EPA-600/J-80-296;
Stock Number PB81-232589
Additional Subjects Viruses ; Dogs ; Electron microscopy ; Veterinary medicine ; Reprints ; Astroviruses ; Coronaviruses ; Parvoviruses
Library Call Number Additional Info Location Last
NTIS  PB81-232589 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 14p
Astrovirus-like, coronavirus-like, and parvovirus-like particles were detected through electron microscopic (EM) examination of loose and diarrheal stools from a litter of beagle pups. Banding pattern obtained from equilibrium centrifugations in CsCl supported the EM identification. Densities associated with the identified particles were: 1.34g/ml for astrovirus, 1.39 g/ml for 'full' parvovirus, and 1.24-1.26 g/ml for 'typical' coronavirus. Convalescent sera from pups aggregated these three particle types as observed by immunoelectron microscopy (IEM). Only coronavirus-like particles were later detected in formed stools from these same pups. Coronavirus and parvo-like viruses are recognized agents of canine viral enteritis, however, astrovirus has not been previously reported in dogs.