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RECORD NUMBER: 43 OF 467

OLS Field Name OLS Field Data
Main Title Application of high performance liquid chromatography/mass spectrometry to environmental analysis /
Author Betowski, L. D. ; Jones, T. L.
Other Authors
Author Title of a Work
Jones, T.L.,
CORP Author Environmental Monitoring Systems Lab., Las Vegas, NV.
Publisher U.S. Environmental Protection Agency, Environmental Monitoring Systems Laboratory,
Year Published 1989
Report Number EPA/600-S4-89-033; EPA/600/4-89/033
Stock Number PB90-116963
OCLC Number 40828486
Subjects Pollution--Analysis. ; High performance liquid chromatography. ; Mass spectrometry.
Additional Subjects Mass spectroscopy ; Chemical analysis ; Herbicides ; Azo dyes ; Chlorine organic compounds ; Design criteria ; Performance evaluation ; Ionization ; Particle beams ; Environmental monitoring ; High performance liquid chromatography ; Phenyls ; Dischargers
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi/94003IKB.PDF?Dockey=94003IKB.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJBD ARCHIVE EPA 600-S4-89-033 In Binder Headquarters Library/Washington,DC 04/25/2018
EJBD  EPA 600-S4-89-033 In Binder Headquarters Library/Washington,DC 11/14/2018
NTIS  PB90-116963 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 3 pages ; 28 cm
Abstract
High performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) is described for the analysis of samples for environmental pollutants. During the course of the work different techniques were used to increase both the sensitivity and specificity of HPLC/MS. These included the utilization of two different interfaces for the mass spectrometer, the thermospray and the particle beam systems. Refinements to the thermospray system were made with the use of a wire-repeller to enhance sensitivity and also to increase the structural information obtained from mass spectra. The operation of the instrument in the discharge negative ionization mode further increased the specificity of these techniques as did the use of a triple quadrupole mass spectrometer in the HPLC/MS system. Two different sets of compounds were used in the study. Organic dyes were used to test the improvements in the system. Since work was performed with dyes previously and since dye compounds encompass a variety of structural functionalities, the dyes made good test compounds. Chlorinated herbicides were studied in an effort to analyze for these compounds directly without having to prepare derivatives before separation.
Notes
Jones, T.L. Caption title. At head of title: Project summary. L.D. Betowski, also Project Officer. "December 1989." "EPA/600-S4-89-033."
Contents Notes
High performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) is described for the analysis of samples for environmental pollutants. During the course of this work different techniques were used to increase both the sensitivity and specificity of HPLC/MS. These included the utilization of two different interfaces for the mass spectrometer - the thermospray and the particle beam systems. Refinements to the thermospray system were made with the use of a wire-repeller to enhance sensitivity and also to increase the structural information obtained from mass spectra. The operation of the instrument in the discharge negative ionization mode further increased the specificity of these techniques as did the use of a triple quadrupole mass spectrometer in the HPLC/MS system. Two different sets of compounds were used in this study. Organic dyes were used to test the improvements in the system. Since work was performed with dyes previously and since dye compounds encompass a variety of structural functionalities, the dyes made good test compounds. Chlorinated herbicides were studied in an effort to analyze for these compounds directly without having to prepare derivatives before separation.