Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Drug toxicokinetics
Other Authors
Author Title of a Work
Welling, Peter G.
De la Iglesia, Felix A.
Publisher M. Dekker,
Year Published 1993
OCLC Number 27813419
ISBN 0824790197 (alk. paper)
Subjects Drugs--Toxicology ; Pharmacokinetics ; Drugs--toxicity ; Pharmacokinetics
Internet Access
Description Access URL
Publisher description
Table of contents
Library Call Number Additional Info Location Last
EKBM  RA1238.D8 1993 Research Triangle Park Library/RTP, NC 02/21/2006
Collation xviii, 408 p. : ill., charts ; 24 cm.
Includes bibliographical references and index.
Contents Notes
Analytical method considerations for toxicokinetic studies / D. Scott Wright -- Pharmacokinetic principles: linear and nonlinear / Peter G. Welling -- Biotransformation of xenobiotics to chemically reactive metabolites / Neal Castagnoli, Jr. and Kay P. Castagnoli -- Role of toxicokinetics in dose selection for carcinogenicity studies / Mitchell N. Cayen and Hugh E. Black -- Toxicokinetic study design and integrated programs / Eva Halperin-Walega, Avraham Yacobi and Vijay K. Batra -- Role of toxicokinetics in toxicity testing / L.F. Chasseaud -- Relation between toxicity and kinetics and models of renal disease / Norberto Perico and Silvio Garattini -- Route of administration and toxicity / Lloyd A. Dethloff -- Genetic variations in humans and toxicokinetics / Bert N. La Du, Jr. -- Comparative histokinetic and xenodynamic considerations in toxicity / Michael J. Iatropoulos -- Toxicokinetics of anticancer compounds / Lloyd R. Whitfield and David G. Pegg -- Toxicokinetics of chemical carcinogens / Anthony J. Streeter. (cont.) Application of toxicokinetic principles in the development of antiatherosclerotic compounds / Robert L. Susick and Thomas Woolf -- Toxicokinetics of drugs acting on the central nervous system / D. Scott Wright, Steven E. Rose and John R. MacDonald -- Toxicokinetics of antibacterial agents: preclinical perspective / Robert D. Smyth and Robert J. Smyth -- Perspective and future directions of toxicokinetics in drug development / Felix A. de la Iglesia.