At head of title: Biological Council, the Co-ordinating Committee for Symposia on Drug Action. Meeting held at the Middlesex Hospital Medical School, April 13-14, 1970 and sponsored by the Biochemical Society and others. Includes bibliographical references and index.
Reactions with enzymes -- Inhibition Patterns of Monoamine Oxidase Isoenzymes: Clinical Implications / M. Sandler, G. G. S. Collins, M. B. H. Youdim -- Monoamine Oxidases and Their Inhibitors / K. F. Tipton -- Some New Effects of Anticholinesterases in the Whole Animal, with Special Emphasis on the Hypothermia Inducing Action in the Rat / E. Meeter -- Mechanism of Inhibition of Glutamine Synthetase by Methionine Sulphoximine / A. Meister, R. A. Ronzio, W. B. Rowe, J. D. Gass, S. L. N. Rao -- Reactions with Proteins -- Effect of Lathyrogenic Compounds on the Cross-Linking of Collagen and Elastin in Vivo / C. I. Levene -- The Capacity of Aspirin to Acetylate Proteins in Vitro and in Vivo / R. S. Farr -- Role of Immune Reactions in Response to Toxic Metals / J. L. Turk -- Binding of Beryllium to Proteins / Elsa Reiner -- Cell Injury -- Liver Cell Injury by Beryllium / H. P. Witschi -- Ribonucleic Acid Polymerase in Nuclear Damage / F. Stirpe, F. Novello -- Cell Suicide and Cell Death / E. Farber, R. S. Verbin, M. Lieberman -- Amoeba Proteus as a Cell Model in Toxicology / Muriel J. Ord -- Lethal synthesis -- Antimetabolic Action of 6-Aminonicotinamide on the Pentose Phosphate Pathway in the Brain / H. Herken -- Mode of Action of Hypoglycin and Related Compounds / H. S. A. Sherratt, P. C. Holland, Judith Marley, A. E. Senior -- Conversion by the Liver of Inactive Molecules into Toxic Molecules / A. E. M. McLean -- The Role of the Gut Flora in the Conversion of Inactive Compounds to Active Metabolites / R. L. Smith. The papers in this book illustrate the inter-play between the acquisition of knowledge of toxic mechanisms and a better understanding of physiological processes.