Record Display for the EPA National Library Catalog
RECORD NUMBER: 546 OF 1335Main Title | Evaluation of the potential carcinogenicity of safrole (94-59-7) / | |||||||||||
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CORP Author | Environmental Monitoring and Services, Inc., Washington, DC. ;Syracuse Research Corp., NY.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. | |||||||||||
Publisher | U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ; | |||||||||||
Year Published | 1988 | |||||||||||
Report Number | EPA/600/8-91/178; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-173 | |||||||||||
Stock Number | PB93-201291 | |||||||||||
Subjects | Safrole--Carcinogenicity | |||||||||||
Additional Subjects | Safrole ; Organic compounds ; Toxicity ; Risk assessment ; Public health ; Exposure ; Hazardous materials ; Neoplasms ; Tolerances(Physiology) ; Carcinogenicity ; Dose-response relationships ; CAS: 94-59-7 | |||||||||||
Holdings |
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Collation | 27 pages ; 28 cm | |||||||||||
Abstract | Safrole is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient', and there are 'No Data' in humans for this compound. The potency factor (F) for safrole is estimated to be 0.18 (mg/kg/day)-1, placing it in potency group 3 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, safrole is assigned a 'LOW' hazard ranking. |
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Notes | Cover title. "June 1988." Includes bibliographical references. Microfiche. |