Record Display for the EPA National Library Catalog

RECORD NUMBER: 489 OF 1173

OLS Field Name OLS Field Data
Main Title Guidance for Safety Testing of Baculoviruses.
CORP Author Environmental Protection Agency, Washington, D.C.
Year Published 1975
Stock Number PB-275 931
Additional Subjects Viruses ; Insect control ; Pest control ; Guidelines ; Exposure ; Safety ; Dosage ; Experimental data ; Skin(Anatomy) ; Toxicity ; Pathology ; Eye(Anatomy) ; Tests ; Respiration ; Tissues(Biology) ; Cultures(Biology) ; Monitors ; Sensitizing ; Animals ; Birds ; Plants(Botany) ; Reprints ; Biological pest control ; Insect viruses
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB-275 931 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 6p
Abstract
The following guidance summarizes the data presently required by the Agency to show the safety of nuclear polyhedrosis and granulosis virus insecticides. When testing the safety of insect viruses, primary emphasis must be given to their pathogenicity and not to their toxicity. Pathogenicity is the capability of the microorganism to infect or reproduce, or to cause overt or covert changes, in animals or animal tissue other than target insects. Toxicity means that microorganisms, and/or their by-products, harm the test animal without actual multiplication such as in certain adverse immunological reactions.