Record Display for the EPA National Library Catalog

RECORD NUMBER: 174 OF 1173

OLS Field Name OLS Field Data
Main Title Chemical of current interest propylene oxide : health and environmental effects profile /
Author Meylan, W. ; Papa, L. ; De Rosa, C. T. ; Stara, J. F.
Other Authors
Author Title of a Work
Papa, L.
DeRosa, C. T.
Stara, J. F.
CORP Author Environmental Protection Agency, Cincinnati, OH. Environmental Criteria and Assessment Office. ;Syracuse Research Corp., NY. Center for Chemical Hazard Assessment.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Environmental Criteria and Assessment Office,
Year Published 1986
Report Number EPA/600/J-86/502
Stock Number PB89-201933
OCLC Number 44718552
Additional Subjects Propylene oxide ; Toxicology ; Water pollution ; Chemical properties ; Environmental transport ; Industries ; Exposure ; Carcinogens ; Rodents ; Dosage ; Risk ; Assessments ; Reprints ; Occupational health and safety
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB89-201933 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 44 pages ; 28 cm
Abstract
The article reviews all of the relevant information on propylene oxide including physical and chemical properties, environmental fate and transport processes, exposure (water, food, inhalation and dermal), pharmacokinetics, effects (carcinogenicity, mutagenicity, teratogenicity, other reproductive effects and chronic toxicity), aquatic toxicity, existing guidelines and standards, and develops risk assessments. The available toxicological data regarding propylene oxide indicate that the compound is a contact carcinogen in rodents, causing stomach tumors following ingestion and nasal tumors after inhalation exposure. Applying the cancer guidelines, propylene oxide is most appropriately classified as a group B2 chemical.
Notes
"Journal article." "EPA/600/J-86/502." "Published in Toxicology and Industrial Health, 2(3):219-260 (1986)." Microfiche.