Record Display for the EPA National Library Catalog

RECORD NUMBER: 167 OF 1146

OLS Field Name OLS Field Data
Main Title Cardiovascular Effects of o,p'-DDD.
Author Cueto, Jr., Cipriano ;
CORP Author Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.
Year Published 1970
Stock Number PB-277 613
Additional Subjects Pesticides ; Epinephrine ; Norepinephrine ; Insecticides ; Cardiovascular system ; Toxicology ; Dogs ; Laboratory animals ; Experimental data ; Dosage ; Responses ; Histamines ; Blood pressure ; Blood plasma ; Histology ; Bioassay ; Reprints ; DDD insecticide ; Glucocorticoids ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB-277 613 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 2p
Abstract
Daily oral administation of o,p'-DDD to dogs produced glucocorticoid deficiency. Blood pressure and heart contractile force and rate response to graded doses of epinephrine and norepinephrine were determined in treated and untreated dogs. Vasopressor and cardioaccelerator responses to ouabain were similar in treated and untreated dogs. The induced glucocorticoid deficiency produced little apparent direct circulatory effect but diminished the ability to withstand stressful procedures such as thoracotomy and multiple injections of vasopressor amines.