Record Display for the EPA National Library Catalog

RECORD NUMBER: 8 OF 29

OLS Field Name OLS Field Data
Main Title Evaluation of Triethanolamine 99 in the Rat Hepatocyte Unscheduled Dna Synthesis Assay (Sanitized).
CORP Author Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 86-890001201S
Stock Number OTS0520713
Additional Subjects Toxicology ; Health effects ; Triethanolamine (102-71-6) ; Genotoxicity ; Dna Effects ; Mammals ; Rats ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 102-71-6
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NTIS  OTS0520713 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/10/2010
Collation 16p
Abstract
Genotoxicity of triethanolamine was evaluated in the rat hepatocyte primary culture/DNA repair assay. The compound was tested at concentrations of 1x10E-8, 1x10E-7, 1x10E-6, 1x10E-5, 1x10E-4, 1x10E-3, 1x10E-2, and 1x10E-1 M in Williams Medium E. The negative control group was cell cultures exposed to the medium only. The positive control groups were cell cultures exposed to the medium plus 2-acetylaminofluorene or 9,10-dimethyl-1,2-benzanthracene (1x10E-6, 1x10E-5, and 1x10E-4 M), in 1% DMSO. The treatment was cytotoxic to cell cultures at 1x10E-1 M. The treatment had no effect on the rate of DNA repair, indicating a lack of genotoxicity of triethanolamine in this cell culture assay.