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RECORD NUMBER: 204 OF 351

OLS Field Name OLS Field Data
Main Title Mutagenic Properties of Drinking Water Disinfectants and By-Products.
Author Meier, J. R. ; Bull, R. J. ;
CORP Author Health Effects Research Lab., Cincinnati, OH.
Year Published 1984
Report Number EPA/600/D-84/224;
Stock Number PB84-246321
Additional Subjects Disinfectants ; Mutagens ; Potable water ; Water treatment ; Carcinogens ; Chemical compounds ; Byproducts ; Chlorination ; Substitutes ; Toxicology ; Laboratory animals ; In vitro analysis ; In vivo analysis ; Public health ; Risks ; Health risks ; Ames test
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB84-246321 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 34p
Abstract
The identification of a number of mutagenic and carcinogenic chemicals in our public water supplies has raised concern over potential genetic and carcinogenic hazards to the human population. There is growing evidence to indicate that these chemicals are produced during water chlorination, and consequently alternative strategies for water disinfection are being considered. Unfortunately, it is not known to what extent the mutagenic activity in chlorinated drinking water, and the associated potential health risks, are accounted for by chemicals identified thus far. The authors laboratory has been exploring the use of humic acid for studying the mutagenic and carcinogenic properties of disinfection by-products. The present report extends our findings on the mutagenic properties of chlorinated humic acids in the Ames test and includes results from studies on the ability of chlorinated and non-chlorinated humic acids. Studies are also being conducted on the toxicological properties of drinking water samples prepared using alternative techniques for disinfection and post-disinfection treatment. Preliminary results on the mutagenic activities of these samples are discussed.