Record Display for the EPA National Library Catalog
RECORD NUMBER: 75 OF 200
|OLS Field Name||OLS Field Data|
|Main Title||Evaluation of the potential carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (1746-01-6) /|
|CORP Author||Environmental Monitoring and Services, Inc., Washington, DC. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.|
|Publisher||U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;|
|Report Number||EPA/600/8-91/181; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-176|
|Additional Subjects||Toxicity ; Risk assessment ; Public health ; Exposure ; Hazardous materials ; Neoplasms ; Tolerances(Physiology) ; Dibenzodioxin/tetrachloro ; Carcinogenicity ; Dose-response relationships ; CAS: 1746-01-6|
|Collation||25 pages ; 28 cm|
2,3,7,8-Tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient', and the evidence from human studies is 'Inadequate'. The potency factor (F) for 2,3,7,8-TCDD is estimated to be 659,000 (mg/kg/day)-1, placing it in potency group 1 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, 2,3,7,8-TCDD is assigned a 'HIGH' hazard ranking.
Cover title. "June 1988." Includes bibliographical references. Microfiche.