Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Comparative Analysis of the Electrostatic Potentials of Dibenzofuran and Some Dibenzo-p-dioxins.
Author Murray, J. S. ; Zilles, B. A. ; Jayasuriya, K. ; Politzer, P. ;
CORP Author New Orleans Univ., LA. Dept. of Chemistry.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher c1986
Year Published 1986
Report Number EPA/600/J-86/514;
Stock Number PB90-117144
Additional Subjects Electrostatics ; Furans ; Graphs(Charts) ; Toxicity ; Measurement ; Reprints ; Dioxin/tetrachloro-dibenzo ; Biological effects
Library Call Number Additional Info Location Last
NTIS  PB90-117144 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/10/1990
Collation 6p
Electrostatic potential maps of dibenzofuran, dibenzo-p-dioxin, 2,8-dichloro-3,7-dimethyldibenzo-p-dioxin, 2,3,7,8-tetrafluorodibenzo-p-dioxin, and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are presented and compared. The biological activities of the molecules increase from zero for the first two to very strong for the highly toxic TCDD. The analysis of the electrostatic potentials suggests certain key features that may be necessary for the effective interaction of the classes of compounds with a cytosolic receptor, which is believed to be the initial step leading to various toxic responses and other biological activity. (Copyright (c) 1986 American Chemical Society.)