Record Display for the EPA National Library Catalog

RECORD NUMBER: 4 OF 35

OLS Field Name OLS Field Data
Main Title Battery of Acute Toxicity Tests with Cover Letter.
CORP Author Food and Drug Research Labs., Inc., Conshohocken, PA. ;Rohm and Haas Co., Philadelphia, PA. Research Labs.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 23 Feb 1983
Year Published 1983
Report Number 878213508;
Stock Number OTS-0205842
Additional Subjects Toxicity ; Testing ; Dermal absorption ; Oral dosage ; Skin(Anatomy) ; Eye irritation ; Mortality ; Inhalation ; Respiratory distress ; Rats ; Rabbits ; Laboratory animals ; Exposure ; 4-(1,1,3,3-tetramethyl butyl)
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  OTS-0205842 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 07/09/2008
Collation 40p
Abstract
Six New Zealand albino rabbits, 2 to 3 kg, were closely clipped over the back and sides with an Oster electric clipper. A 0.5 gram portion of the test material was introduced under a 1.5 inch, 12-ply gauze patch placed directly over the test site and held in place with Dermicel tape. The rabbits were wrapped with rubber damming for an exposure period of 4 hours. Slight erythema was observed in 4 animals after 4 hours. All signs of irritation had disappeared in 24 hours. Rohm and Haas Company sample '6-8815, Octylphenol,' when applied to the skin of New Zealand albino rabbits in the quantity of 0.5 ml produced no signs of corrosivity.