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RECORD NUMBER: 28 OF 35

OLS Field Name OLS Field Data
Main Title Toxicological Review of Acrylamide (CAS No. 79-06-1) in Support of Summary Information on the Integrated Risk Information System (IRIS).
CORP Author Environmental Protection Agency, Washington, DC. National Center for Environmental Assessment.
Year Published 2010
Report Number EPA/635/R-07/009F
Stock Number PB2010-113840
Additional Subjects Toxicity ; Acrylamide ; Health effects ; Risk assessment ; Environmental exposure ; Health hazards ; Dose-reponse relationships ; Inhalation ; Oral dosage ; Dermal absorption ; Carcinogens ; Humans ; Epidemiology ; Integrated Risk Information System (IRIS) ; CAS No 79-06-1
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB2010-113840 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/21/2011
Collation 459p
Abstract
This document presents background information and justification for the Integrated Risk Information System (IRIS) Summary of the hazard and dose-response assessment of Acrylamide (AA). IRIS Summaries may include oral reference dose (RfD) and inhalation reference concentration (RfC) values for chronic and other exposure durations, and a carcinogenicity assessment. The RfD and RfC, if derived, provide quantitative information for use in risk assessments for health effects known or assumed to be produced through a nonlinear (presumed threshold) mode of action (MOA). The RfD (expressed in units of mg/kg-day) is defined as an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without an appreciable risk of deleterious effects during a lifetime.