Record Display for the EPA National Library Catalog
RECORD NUMBER: 89 OF 397Main Title | DDT Metabolism: Oxidation of the Metabolite 2,2-bis(p-Chlorophenyl)ethanol by Alcohol Dehydrogenase. | |||||||||||
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Author | Suggs, Joseph E. ; Hawk, Robert E. ; Curley, August ; Boozer, Elizabeth L. ; McKinney., James D. ; | |||||||||||
CORP Author | Food and Drug Administration, Atlanta, Ga. Atlanta Toxicology Branch. ;National Inst. of Environmental Health Sciences, Research Triangle Park, N.C. | |||||||||||
Year Published | 1970 | |||||||||||
Stock Number | PB-278 089 | |||||||||||
Additional Subjects | DDT ; Pesticides ; Insecticides ; Toxicology ; Metabolism ; Oxidation ; Chlorine organic compounds ; Alcohols ; Reprints ; Metabolites ; Toxic substances ; Ethanol/bis(chlorophenyl) ; Dehydrogenases/alcohol | |||||||||||
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Collation | 1p | |||||||||||
Abstract | A metabolite of DDT, 2,2-bis(p-chlorophenyl)ethanol, is a substrate of crystalline liver alcohol dehydrogenase. The oxidation of the substrate was detected spectrophotometrically. The p-nitrophenylhydrazone derivative of the product, 2,2-bis(p-chlorophenyl)acetaldehyde, was identified by comparing its mass spectrum and thin-layer chromatographic behavior with that of an authentic sample. |