Record Display for the EPA National Library Catalog
RECORD NUMBER: 21 OF 47Main Title | Effect of Diphenylhydantoin on Storage of DDT in the Rat. | |||||||||||
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Author | Cranmer., M. F. ; | |||||||||||
CORP Author | Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab. | |||||||||||
Year Published | 1970 | |||||||||||
Stock Number | PB-277 591 | |||||||||||
Additional Subjects | DDT ; Pesticides ; Drugs ; Insecticides ; Storage ; Rats ; Laboratory animals ; Diets ; Enzymes ; Experimental data ; Bioassay ; Pharmacology ; Bioaccumulation ; Reprints ; DDE insecticide ; Pesticide residues ; Hydantoin/diphenyl ; Toxic substances | |||||||||||
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Collation | 1p | |||||||||||
Abstract | Dilantin is a widely used anticonvulsant drug which has been shown to stimulate liver microsomal enzymes and reduce DDT and DDE residues in man. This investigation was undertaken to study the effect of Dilantin on the storage of DDT and DDE in the rat. Dilantin was found to reduce the levels of p,p'-DDT and p,p'-DDE in the fat and to increase liver microsomal enzyme activity in all animals except those receiving 10 ppm p,p'-DDT for 14 months. |