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RECORD NUMBER: 11 OF 108

OLS Field Name OLS Field Data
Main Title Colonization Potentials of Male and Female E. coli K 12 Strains E coli B and Human Fecal E. coli Strains in the Mouse GI Tract.
Author Cohen, Paul S. ; Pilsucki, Robert W. ; Myhal, M. Lynn ; Rosen, Craig A. ; Laux., David C. ;
CORP Author Rhode Island Univ., Kingston. Dept. of Microbiology.;Health Effects Research Lab., Cincinnati, OH.
Year Published 1980
Report Number EPA-R-805488-01; EPA-600/J-80-222;
Stock Number PB81-166597
Additional Subjects Escherichia coli ; Cultures(Biology) ; Intestines ; Males ; Females ; Humans ; Mice ; Microorganisms ; Reprints ; Animal models
Holdings
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Status
NTIS  PB81-166597 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 10p
Abstract
In order to compare the colonization potentials of individual Escherichia coli strains, the authors developed a simple animal system in which both freshly isolated human strains and laboratory strains (i.e. E. coli B and E. coli K 12 strains) survive in the large intestine for long periods of time when fed to these animals alone. Once this condition was achieved the colonization potential of each E. coli strain relative to others was determined by feeding the animals two or more strains simultaneously. In the present investigation the authors report that mice whose normal facultative microflora is reduced by the addition of streptomycin to their drinking water can be used to compare the intrinsic large intestine colonization potentials of E. coli strains, including E. coli B male and female strains of E. coli K 12, and E. coli strains recently isolated from human feces.