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RECORD NUMBER: 28 OF 28

OLS Field Name OLS Field Data
Main Title Updated mutagenicity and carcinogenicity assessment of cadmium.
CORP Author United States. Environmental Protection Agency. Office of Health and Environmental Assessment.; Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment,
Year Published 1985
Report Number EPA-600/8-83-025F
Stock Number PB85-243533
OCLC Number 12959913
Subjects Cadmium--Toxicology. ; Environmental health. ; Carcinogens.
Additional Subjects Cadmium--Toxicology ; Environmental health ; Carcinogens ; Toxicology ; Assessments ; Public health ; Risk ; Exposure ; Metals ; Smoking ; Food ; Concentrations(Compositions) ; Physiological effects ; Heavy metals ; Cigarette smoking ; Bioaccumulation ; Toxic substances ; Health risks
Internet Access
Description Access URL
EPA-600/8-83-025F https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=30001BFW.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EHAM  RA1231 .C3U6 1983 Region 1 Library/Boston,MA 04/29/2016
EJAD  EPA 600/8-83-025F Region 3 Library/Philadelphia, PA 12/10/1993
EJBD ARCHIVE EPA 600-8-83-025F Headquarters Library/Washington,DC 11/02/2009
EJED  EPA 600/8-83-025F OCSPP Chemical Library/Washington,DC 01/01/1988
EKAM  EPA-600/8-83-025F Region 4 Library/Atlanta,GA 10/13/1995
EKBD  EPA-600/8-83-025f Research Triangle Park Library/RTP, NC 04/11/1997
ERAD  EPA 600/8-83-025F Region 9 Library/San Francisco,CA 02/19/2013
ESAD  EPA 600-8-83-025F Region 10 Library/Seattle,WA 03/23/2010
NTIS  PB85-243533 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation x, 192 pages : illustrations ; 28 cm
Abstract
The document evaluates the mutagenicity and carcinogenicity of cadmium, supplementing an earlier document (Health Assessment Document for Cadmium, May 1981) which dealt with all health effects. Since the earlier document was prepared, a rat inhalation carcinogenicity study has been reported and several epidemiology and mutagenicity papers have been published. This document concludes that: (1) there is mixed evidence on the mutagenicity of various cadmium salts; (2) cadmium chloride aerosol induces lung cancer in rats; (3) injected cadmium salts induce injection site sarcomas and testicular tumors in both mice and rats; (4) there is limited epidemiologic evidence that inhaled cadmium is dose-related to lung cancer in exposed workers; (5) there is no evidence that cadmium is carcinogenic via ingestion, which is a major route of human exposure, and the upper limit of potency via ingestion is at least 100 times less than via inhalation.
Notes
"EPA-600/8-83-025F." "June 1985." "Final." "Addendum to the Health Assessment Document for Cadmium (May 1981)--EPA-600/8-81-023."
Contents Notes
"This document evaluates the mutagenicity and carcinogen!city of cadmium, supplementing an earlier document (Health Assessment Document for Cadmium, May 1981) which dealt with all health effects. Since the earlier document was prepared, a rat inhalation carcinogenicity study has been reported and several epidemiology and mutagenicity papers have been published. This document concludes that: (1) there is mixed evidence on the mutagenicity of various cadmium salts; (2) cadmium chloride aerosol induces lung cancer in rats; (3) injected cadmium salts induce injection site sarcomas and testicular tumors in both mice and rats; (4) there is limited epidemiologic evidence that inhaled cadmium is dose-related to lung cancer in exposed workers; (5) there is no evidence that cadmium is carcinogenic via ingestion, which is a major route of human exposure, and the upper limit of potency via ingestion is at least 100 times less than via inhalation."--Abstract