Introduction -- Social and economic setting -- American Indian peoples -- Biophysical setting and landscape dynamics -- Terrestrial ecology -- Aquatic species and habitats -- Ecosystem integrity -- The future of the Basin : analysis of management options -- Conclusion : from science to management. The Status of the Interior Columbia Basin is a summary of the scientific findings from the Interior Columbia Basin Ecosystem Management Project. The Interior Columbia Basin includes some 145 million acres within the northwestern United States. Over 75 million acres of this area are managed by the USDA Forest Service or the USDI Bureau of Land Management. A framework for ecosystem management is described that assumes the broad purpose is to maintain the integrity of ecosystems over time and space. An integrated scientific assessment links landscape, aquatic, terrestrial, social, and economic characterizations to describe the biophysical and social systems. Ecosystem conditions within the Basin have changed substantially within the last 100 years. The status of ecosystems is described in terms of current conditions and trends under three broadly defined management options. The scientific information brought forward will be used in decision-making, and may potentially amend Forest Service and Bureau of Land Management plans within the Basin. The information highlighted here represents an integrated view of biophysical and socioeconomic elements at a scale never before attempted. The risks and opportunities are characterized in the broad context of the Basin for managers and the public to use as a foundation for discussion about future management.