Record Display for the EPA National Library Catalog

RECORD NUMBER: 12 OF 40

OLS Field Name OLS Field Data
Main Title Effects of Selected Water Toxicants on the in vitro Activity of Fish Carbonic Anhydrase.
Author Christensen, G. M. ; Tucker., J. H. ;
CORP Author Environmental Research Lab.-Duluth, Minn.
Year Published 1975
Report Number EPA/600/J-76/010;
Stock Number PB-265 284
Additional Subjects Toxicity ; Catfishes ; Fishes ; Carbonic anhydrase inhibitors ; Metals ; Toxicology ; Physiochemical properties ; Water quality ; Dosage ; Water pollution ; In vitro analysis ; Enzyme inhibitors ; Pesticides ; Cations ; Anions ; Experimental data ; Blood ; Erythrocytes ; Physiochemical properties ; Reprints ; Ictalurus punctatus ; Water pollution effects(Animals) ; Chemicals ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB-265 284 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 14p
Abstract
Carbonic anhydrase (CA, carbonate hydro-lyase EC 4.2.1.1) from lysed red blood cells of the channel catfish (Ictalurus punctatus) was studied to determine physico-chemical kinetic properties and relative sensitivity to 56 chemicals of significance in water quality research. In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds. Dose-response curves were qualitatively similar in most cases.