Record Display for the EPA National Library Catalog
RECORD NUMBER: 4 OF 56
|OLS Field Name||OLS Field Data|
|Main Title||Cardiac Sensitization Studies in Dogs with Myocardial Infarctions.|
|Publisher||Aerospace Medical Research Lab,|
|Report Number||AMRL-TR-74-125-Paper-10; AD-A011 859; AMRL-TR-74-125-PAPER-10|
|Subjects||Civil Engineering. ; Environmental Health and Safety. ; Halogenated hydrocarbons. ; Myocardial infarction. ; Industrial medicine. ; Experimental data. ; Exposure(physiology) ; Dogs. ; Laboratory animals. ; Cardiovascular diseases. ; Arrhythmia. ; Epinephrine.|
Prepared in cooperation with Du Pont de Nemours (E.I.) and Co., Wilmington, Del. "AD-A011 859." "AMRL-TR-74-125-PAPER-10." "Filmed 8-13-75 NTIS." Microfiche.
In man, myocardial infarction is the most serious form of ischemic cardiovascular disease and, because of its frequent occurrence, it is the single most important type of heart disease. Since myocardial infarction is common in the human population, the authors attempted to determine whether such a condition might place an individual, exposed to high halocarbon concentrations, at greater risk from an epinephrine-induced cardiac arrhythmia. Such exposure conditions could occur in the chemical industry, or in the refrigeration and aerosol industries. Using the dog as an animal model for myocardial infarction, results imply that such an individual, having recovered from myocardial infarction and able to return to work, may be at no greater risk from cardiac sensitization than the normal healthy individual.