Record Display for the EPA National Library Catalog
RECORD NUMBER: 453 OF 992Main Title | Initial Submission: Letter from Degussa Corp. to USEPA re: Summary of Skin Painting Study of Quab 188, 65.79% 3-Chloro-2-Hydroxypro pyltrimethylammonium Chloride, dated 11/22/1996. | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CORP Author | Degussa Corp., Allendale, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
Year Published | 1996 | |||||||||||
Report Number | 88970000067 | |||||||||||
Stock Number | OTS0559054 | |||||||||||
Additional Subjects | Toxicology ; Health effects ; Toxic substances ; 3-chloro-2-hydroxypro pyltrimethylammonium chloride ; Chronic toxicity ; Carcinogenicity ; Mammals ; Mice ; Dermal ; CAS No 3327-22-8 | |||||||||||
Holdings |
|
|||||||||||
Collation | 15p | |||||||||||
Abstract | Groups of 50 NMRI-mice of each sex were treated twice weekly with 0.2 mlof 0, 0.018, and 0.18 ml of 3-Chloro-2-hydroxypropyl- trimethylammonium chloride dissolved in a 10% aqueous ethanol solution. This corresponds to doses of 0, 13.8, and 138 mglanimal applied to the clipped dorsal skin (2 cm2) of the animals. The study was terminated after 89 weeks forfemale animals and 105 weeks for male animals when the 25% survival limit was reached. |