Record Display for the EPA National Library Catalog
RECORD NUMBER: 1 OF 1Main Title | Evaluation of the potential carcinogenicity of N-Nitrosodiethanolamine (1116-54-7) / | |||||||||||
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CORP Author | Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. | |||||||||||
Publisher | U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ; | |||||||||||
Year Published | 1988 | |||||||||||
Report Number | EPA-68-03-3112; EPA-68-03-3182; EPA/600/8-91/159; OHEA-C-073-147 | |||||||||||
Stock Number | PB93-196434 | |||||||||||
Subjects | N-nitrosodiethanolamine--carcinogenicity | |||||||||||
Additional Subjects | Toxicity ; Risk assessment ; Public health ; Exposure ; Hazardous materials ; Neoplasms ; Tolerances(Physiology) ; Diethanolamine/N-nitroso ; Carcinogenicity ; Dose-response relationships ; CAS: 1116-54-7 | |||||||||||
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Collation | 22 pages ; 28 cm | |||||||||||
Abstract | N-Nitrosodiethanolamine is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient', and the evidence from human studies is 'No Data'. The results of the bioassay test used to calculate the potency factor (F) for N-nitrosodiethanolamine suggest that the experimental dose delivered to the test animals was too high (i.e., all treated animals got tumors). Hence, under the CAG's methodology for evaluating potential carcinogens N-nitrosodiethanolamine is assigned to potency group 1. Combining the weight-of-evidence group and the potency group, N-nitrosodiethanolamine is assigned a 'HIGH' hazard ranking. |
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Notes | Cover title. "June 1988." Includes bibliographical references. Microfiche. |