||In Vitro Mammalian Cell Gene Mutation Test with an Independent Repeat Assay using Vapor Phase Exposure to 1,6-Hexamethylene Diisocyanate, with Cover Letter dated 09/30/1998.
||Microbiological Associates, Bethesda, MD.; Chemical Manufacturers Association, Washington, DC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
6-hexamethylene diisocyanate ;
Gene mutations ;
In vitro ;
CAS No 822-06-0
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The test article, 1,6 - Hexamethylene diisocyanate, was tested in the CHO/HGPRT Mutation Assay in the absence and presence of Aroclor-induced rat liver S9. The preliminary toxicity assay was used to establish the dose range for the initial mutagenesis assay. The initial and independent repeat mutagenesis assays were used to evaluate the mutagenic potential of the test article.